Molecular characterization of fertilization markers in ejaculate.
Recruiting
- Conditions
- N46Male infertility
- Registration Number
- DRKS00029986
- Lead Sponsor
- niklinik Köln, Klinik für Urologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 100
Inclusion Criteria
All ejaculate samples obtained for diagnostic purposes in the context of a fertility clinic.
Exclusion Criteria
post vasectomy
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary aim of the study is to identify markers by retrospective histo/molecular genetic analysis of mRNA, miRNA and proteins from purified ejaculate samples using proteins known from the literature. The analysis is carried out from diagnostic surplus material of ejaculate analyses performed in our department. Comparison of the occurrence between cohort A (normozoospermia) and B (restrictions in the spermiogram). No experimental therapy is performed and no additional measures are taken.
- Secondary Outcome Measures
Name Time Method