Assessing the microcirculation and its response to different fluid volumes in children with septic shock- A randomized controlled trial

AIIMS0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年11月13日

试验速览

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•All children 2 months to less than 17 years of age admitted to the emergency/ICU with a diagnosis of septic shock will be eligible for inclusion.
•At least 3 of the following criteria should be present of which criteria no.1 is essential criteria – 1) capillary refill time 2 seconds or less than 1 second, 2) cold extremities 3) feeble or bounding peripheral pulses 4) hypotension (systolic BP less than 5th centile as per PALS guidelines) and 5) history of decreased urine output

•1.Children who received boluses before enrolment
•2. Children with chronic kidney disease / fulminant myocarditis / dengue shock syndrome /
•3. Children with severe anemia (Hb <5 gm/dL) or severe acute malnutrition (weight/height <-3 SD Z score as per WHO charts) malaria
•4. Post-arrest shock and cardiac dysfunction
•5. Moribund patients with anticipated survival of < 24 hours

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