Dietary changes and markers of stress and depression in freshman bachelor students at Wageningen University
Recruiting
- Conditions
- stress, despressie en voedingsstatusmental healthnutritional status
- Registration Number
- NL-OMON53272
- Lead Sponsor
- Wageningen Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 225
Inclusion Criteria
• First-time enrolled in a bachelor study at Wageningen University
• Aged 16 years or older during the AID
• Dutch-speaking
Exclusion Criteria
None
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main endpoints are changes in dietary habits towards a plant-based diet and<br /><br>changes in stress levels. Diet changes will be expressed as changes in defined<br /><br>meat-based diet categories (questionnaire) and as changes in the consumption of<br /><br>plant protein as a percentage of total protein (FFQ). Stress levels will be<br /><br>assessed with two questionnaires and one biomarker (hair cortisol). Urinary<br /><br>serotonin concentrations will be used as a potential marker for depression and<br /><br>compared to scores on the validated HADS questionnaire for depression and<br /><br>anxiety. </p><br>
- Secondary Outcome Measures
Name Time Method <p>To assess the nutritional impact of dietary changes, nutritional status over<br /><br>time will be measured crudely as Hb from a capillary (finger) blood sample in<br /><br>all participants and more in-depth (vitamins B6, B12, D, and folic acid) for<br /><br>those who provide a venous blood sample. In the fecal sample at baseline and 6<br /><br>months, pH as a marker of fermentation will be measured. To adjust for<br /><br>confounding variables, additional lifestyle questionnaires and anthropometry<br /><br>will be used. Measurements at 3 and 9 months will be used to study timing of<br /><br>changes.</p><br>