Assessing the Change in Penile Length Following Bilateral Nerve-Sparing Radical Prostatectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 121
- 试验地点
- 1
- 主要终点
- Assess the impact of radical retropubic prostatectomy on penile dimensions.
研究概览
简要总结
Some men complain of changes in the shape or dimensions of their penis after undergoing radical prostatectomy (removal of the prostate) for prostate cancer. Changes in penile dimensions include shortening or decreased girth. Changes in shape include a curvature or bending of the penis, and/or the appearance of indentation. These changes may be associated with formation of scar tissue involving the covering of the erection chambers, known as "plaque". The appearance of indurated plaque and a resultant curvature or indentation is a well described medical condition known as "Peyronie's Disease" and may occur in men who did or did not undergo radical prostatectomy. The purpose of this study is to evaluate these changes in penile shape and dimensions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Males, age 21 years or older (no maximum age limit)
- •Ability and willingness to give informed consent
- •Clinically localized prostate cancer
- •Open, laparoscopic or robotic-assisted radical prostatectomy
- •Must be sexually active (penetrative or non-penetrative sexual encounters, either with a partner or self-stimulation)
排除标准
- •Preoperative / Postoperative pelvic radiation therapy
- •Preoperative / Postoperative hormonal treatment
- •Preoperative Peyronie's disease
- •Preoperative presence of a penile implant
结局指标
主要结局
Assess the impact of radical retropubic prostatectomy on penile dimensions.
时间窗: conclusion of the study
Assess the impact of radical retropubic prostatectomy on the development of Peyronie's Disease.
时间窗: conclusion of the study
次要结局
- Assess the association between penile length change and erectile function.(conclusion of the study)