Skip to main content
Clinical Trials/NCT05529446
NCT05529446
Completed
Not Applicable

Effect of Combination Therapy on Knee Osteoarthritis Pain in Postmenopausal Women

Cairo University1 site in 1 country40 target enrollmentMarch 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Non Specific Knee Osteoarthritis Pain
Sponsor
Cairo University
Enrollment
40
Locations
1
Primary Endpoint
Knee Range Of Motion
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

the aim of this study is to investigate the efficacy of Combination Therapy on Knee Osteoarthritis Pain in Postmenopausal Women

Detailed Description

Osteoarthritis (OA) is the most common musculoskeletal condition affecting the quality of life of older adults. The prevalence of OA is very high 45% in females in comparison to males, especially after menopause due to the hormonal changes. In the physical therapy practice, therapeutic ultrasound (US) is one of the most frequently applied electrotherapeutic modalities in orthopedics physiotherapy. Simultaneous application of two therapeutic modalities at the same site is described as combination therapy (CT). The most commonly used CT is US \& Transcutaneous neuromuscular electrical stimulation (TENS )where this approach was effective in pain modulation .The use of combination therapy is highly preferable because of the advantageous effect both electro-therapy and ultrasound provide simultaneously. There are no current studies on using combination therapy in the treatment of pain in mild to moderate knee osteoarthritis in post-menopausal women and we don't know the proper treatment dose.The study is designed as a prospective, randomized, pre-posttest, controlled trial.where we have two groups Intervention group and control. the intervention group will recieve strengthening exercises in addition to combination therapy 10 minutes for each session, 3 times per week, for 3 weeks.The Control group will recieve the same strengthening exercises as intervention group and sham combination therapy 10 minutes for each session, 3 times per week, for 2 weeks.

Registry
clinicaltrials.gov
Start Date
March 1, 2022
End Date
April 15, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Madonna Noshi Welson Aiad

principle investigator

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Forty women who suffer pain out of mild to moderate knee osteoarthritis
  • Their age will range from 55 to 65
  • At least one year after last menstruation.
  • Their BMI will be ranged from 25 to 35 kg/m2

Exclusion Criteria

  • Neurological disorders.
  • Cardiovascular disorders.
  • Severe knee osteoarthritis
  • Areas of the body where cancerous lesions exist.
  • Any skin impairment at site of application as inflammation, lesion, wounds, infection and swelling.
  • Pacemaker and any metallic implants.

Outcomes

Primary Outcomes

Knee Range Of Motion

Time Frame: up to four weeks

electronic goniometer it measures range of motion objectively assess ROM for extremities and digits

Secondary Outcomes

  • activity of daily living(up to four weeks)

Study Sites (1)

Loading locations...

Similar Trials