NCT01093339已完成不适用
To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure, and if This Effect is Mediated in Gastroesophageal Reflux Disease (GERD)Patients by Altering Appetite Regulation
Southern Arizona VA Health Care System1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2006年8月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to determine if sleep deprivation results in increased esophageal acid exposure in healthy controls and gastroesophageal reflux disease (GERD) patients.
详细描述
To determine if increased esophageal acid exposure is mediated by altering appetite regulation. To assess if there is any relationship between sleep deprivation and the serum level of TNF-alfa (a protein that can be elevated in inflammation).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male/Female - 18-80
- •2 or more episodes of heartburn a week for last 3 months
排除标准
- •Previous upper GI surgery
- •Underlying co-morbidity
- •Narcotic medications
- •Psychotropic's and Benzodiazapines medications
- •Hx of psychological abnormalities
- •Hx of ETOH in previous 6 mos.
- •Diabetes Mellitus
- •Neuropathy
- •Sleep Apnea
- •Co-morbidity that interfere w/sleep
- •Women who are pregnant, or childbearing yrs, not on BC
研究者
研究点 (1)
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