Investigating the effect of levothyroxine therapy on sex hormone levels
Phase 3
Recruiting
- Conditions
- Subclinical hypothyroidism.Subclinical iodine-deficiency hypothyroidism
- Registration Number
- IRCT20181006041252N6
- Lead Sponsor
- Sabzevar University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Women aged 17-40 years with TSH above the maximum normal laboratory range and less than 10 and also T3, T4 normal.
Exclusion Criteria
Irregular ovarian cycles (irregular menstruation)
Pregnancy, breastfeeding, hypothalamic amenorrhoea, known pituitary diseases, and early menopause.
The history of ovarian surgery, polycystic ovary syndrome (PCOS), and the use of hormonal medications.
History of levothyroxine tablets in the last two months.
Dissatisfaction patients to participate in the study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determine the level of Estrogen. Timepoint: At the beginning of the study (before the intervention) and 2 months after starting the intervention. Method of measurement: Use of Luminescence quantitative and ELISA methods.;Determine the level of progesterone. Timepoint: At the beginning of the study (before the intervention) and 2 months after starting the intervention. Method of measurement: Use of Luminescence quantitative and ELISA methods.
- Secondary Outcome Measures
Name Time Method