Prospective Clinical Study on Site Preservation of Alveolar Ridge After Tooth Extraction Before Dental Implantation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 88
- 主要终点
- Changes in the alveolar crest width - central
研究概览
简要总结
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage. After teeth extraction, Geistlich Bio-Oss ® Particles or Bio-Oss ® Collagen are immediately implanted in the teeth extraction socket and covered with Bio-Gide ® collagen membrane for site preservation.Through postoperative follow-up, postoperative clinical and imaging objective indicators, combined with the subjective evaluation of surgeons and patients, and compared with conventional extraction treatment method, the study is aimed to evaluate the effectiveness of different site preservation of alveolar crest preservation, in order to reduce the alveolar bone width and height loss, effectively reduce alveolar bone absorption, or even achieve bone incrementation, thus to get the ideal site preservation effect, to improve the oral implant success rate, improve implant aesthetic score and patient satisfaction, provide more clinical standard reference of the clinical application of site preservation.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients willing to performed site preservation with Geistlich Bio-Oss ® Particles + Bio-Gide ® collagen membrane after tooth extraction;
- •patients willing to performed site preservation with Geistlich Bio-Oss ® Collagen + Bio-Gide ® collagen membrane after tooth extraction;
- •patients willing to performed no site preservation after tooth extraction and only conventional healing.
排除标准
- •patients unwilling to sign the informed consent form and the letter of authorization;
- •patients has a potential systematic diseases;
- •patients had previously been treated with radiation therapy;
- •patients can not re-visit on time.
结局指标
主要结局
Changes in the alveolar crest width - central
时间窗: up to 12 weeks after Dental extraction or site preservation surgery
The central alveolar bone width of the ideal implant site will be measured with CBCT at 3 months after tooth extraction alone or plus site preservation
Changes in the alveolar crest height - central
时间窗: up to 12 weeks after Dental extraction or site preservation surgery
The central alveolar bone height of the ideal implant site will be measured with CBCT at 3 months after tooth extraction or plus site preservation
次要结局
- Changes in the alveolar bone height - different horizontal sites(up to 12 weeks after Dental extraction or site preservation surgery)
- Plaque index (PLI)(up to 12 weeks after Dental extraction or site preservation surgery)
- Bleeding index (BI)(up to 12 weeks after Dental extraction or site preservation surgery)
- Phenotype assessment(up to 12 weeks after Dental extraction or site preservation surgery)
- Soft tissue thickness(up to 12 weeks after Dental extraction or site preservation surgery)
- Changes in the alveolar bone width - different depths(up to 12 weeks after Dental extraction or site preservation surgery)
- Probing depth (PD)(up to 12 weeks after Dental extraction or site preservation surgery)
- Pain degree(up to 12 weeks after Dental extraction or site preservation surgery.)