Synergistic Effects of Low-Dose Caffeine and Taurine on Anaerobic, Neuromuscular, and Cognitive Performance: A Double-Blind Randomized Placebo-Controlled Crossover Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Anaerobic Power
研究概览
简要总结
This study aims to investigate the effects of low-dose caffeine and taurine, administered separately and in combination, on anaerobic, neuromuscular, and cognitive performance. The study is designed as a randomized, double-blind, placebo-controlled crossover trial involving trained man participants. Each participant will complete experimental sessions under different supplementation conditions, including caffeine, taurine, their combination, and placebo. Performance outcomes will include anaerobic power, neuromuscular performance, and cognitive function assessments. The findings will help clarify whether the combined ingestion of caffeine and taurine produces synergistic performance effects compared with isolated supplementation.
详细描述
Caffeine and taurine are commonly consumed ingredients in coffee and energy drinks and are frequently used as ergogenic aids to enhance physical and cognitive performance. Although both compounds have been widely investigated individually, evidence regarding their combined effects remains limited and inconsistent. Understanding whether caffeine and taurine produce synergistic or additive effects is important for clarifying their role in sports performance and supplementation strategies.
The present study is designed as a randomized, double-blind, placebo-controlled crossover trial to examine the isolated and combined effects of low-dose caffeine and taurine on anaerobic, neuromuscular, and cognitive performance in trained individuals. Participants will complete multiple experimental sessions under different supplementation conditions, including caffeine, taurine, their combination, and placebo. During each session, participants will undergo standardized performance assessments to evaluate anaerobic power, neuromuscular performance, and cognitive function. The crossover design allows each participant to serve as their own control, minimizing inter-individual variability. The findings of this study may provide further insight into the potential synergistic effects of caffeine and taurine supplementation on performance outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Male participants aged 18 to 25 years
- •Regularly engaged in strength training at least three days per week for the previous 24 months
- •Apparently healthy with no self-reported cardiovascular, metabolic, neurological, or musculoskeletal disorders
- •Free from injuries affecting skeletal muscles, joints, or tendons during the previous two years
排除标准
- •Use of medications or dietary supplements that may influence physical or cognitive performance
- •Known sensitivity or intolerance to caffeine or taurine
- •Consumption of caffeine or other stimulants within 24 hours prior to the testing sessions
- •Failure to comply with pre-testing instructions or study procedures
研究组 & 干预措施
Caffeine
Participants receive caffeine at a dose of 2 mg/kg body mass in capsule form 60 minutes prior to the performance testing session. Anaerobic, neuromuscular, and cognitive performance outcomes are assessed following supplementation.
干预措施: Caffeine (Dietary Supplement)
Caffeine
Participants receive caffeine at a dose of 2 mg/kg body mass in capsule form 60 minutes prior to the performance testing session. Anaerobic, neuromuscular, and cognitive performance outcomes are assessed following supplementation.
干预措施: Placebo (Dietary Supplement)
Taurine
Participants receive taurine at a dose of 10 mg/kg body mass in capsule form 60 minutes prior to the performance testing session. Anaerobic, neuromuscular, and cognitive performance outcomes are assessed following supplementation.
干预措施: taurine (Dietary Supplement)
Taurine
Participants receive taurine at a dose of 10 mg/kg body mass in capsule form 60 minutes prior to the performance testing session. Anaerobic, neuromuscular, and cognitive performance outcomes are assessed following supplementation.
干预措施: Placebo (Dietary Supplement)
Caffeine + Taurine
Participants receive a combination of caffeine (2 mg/kg) and taurine (10 mg/kg) in capsule form 60 minutes prior to the performance testing session. Performance assessments include anaerobic, neuromuscular, and cognitive outcomes.
干预措施: Caffeine + Taurine (Dietary Supplement)
Plasebo (Maltodextrine 300 mg)
Participants receive a placebo capsule containing maltodextrin (300 mg) 60 minutes prior to the performance testing session. The same performance tests are administered to allow comparison with the supplementation conditions.
干预措施: Placebo (Dietary Supplement)
结局指标
主要结局
Anaerobic Power
时间窗: 60 minutes after supplementation
Anaerobic power measured during the Wingate Anaerobic Test following supplementation conditions (caffeine, taurine, caffeine + taurine, and placebo).
次要结局
- Neuromuscular Performance(60 minutes after supplementation)
研究者
Yakup Kose
Research Assistant
Burdur Mehmet Akif Ersoy University