NCT01820975CompletedNot Applicable
The Manipulation of Dietary Protein Intake on the Anabolic Response in Healthy Young Men
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 28
- Primary Endpoint
- Muscle protein fractional synthetic rate following protein ingestion
Study Overview
Brief Summary
In the present study, the effect of habitual dietary protein on the anabolic response will be investigated.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Aged between 18-35 years
- •Healthy, recreationally active
- •BMI < 30 kg/m2
Exclusion Criteria
- •Allergies to milk proteins (whey or casein)
- •Vegetarians
- •Diagnosed GI tract diseases
- •Arthritic conditions
- •A history of neuromuscular problems
- •Previous participation in amino acid tracer studies
- •Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications
Arms & Interventions
High protein intake
Experimental
High protein intake: large bolus of protein in teh diet the day before testing
Intervention: High protein intake (Dietary Supplement)
No protein intake
Placebo Comparator
No protein in the diet the day before testing
Intervention: Placebo comparator (Other)
Outcomes
Primary Outcomes
Muscle protein fractional synthetic rate following protein ingestion
Time Frame: 3 hours
The ability of the muscle to synthesise new proteins will be assessed over a 3 h period following protein ingestion and will be compared between groups. This only occurs on one occasion.
Secondary Outcomes
No secondary outcomes reported
Investigators
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