Electrophysiological Exams to Test Auditory Cognition and Postural Balance in HTLV-1 Associated Myelopathy (HAM)

niversidade Federal de Minas Gerais0 sitesDecember 27, 2023

Overview

No summary available.

Registry

who.int

Start Date

December 27, 2023

End Date

December 31, 2026

Last Updated

2 years ago

Study Type

Intervention

Sponsor

niversidade Federal de Minas Gerais

•Control group: Composed of individuals with negative serology for HTLV\-1 by the ELISA (Enzyme\-linked\-immunosorbent \-assay) test; Group with HTLV\-1 infection: Composed of former blood donors from Fundação Hemominas with seropositivity defined by the ELISA test and confirmed through WB (Western Blot) or molecular tests (Polymerase Chain Reaction \- PCR); HAM group: individuals with sufficient clinical signs, according to the criteria proposed by the adapted WHO (GRASSI et al, 2011; CASTRO\-COSTA, 2006\), classified according to the adapted Expanded Functional Disability Scale (EDSS) and OSAME presenting classification from two on both scales.

•Positive serology for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), positive Venereal Disease Research Laboratory (VDRL) test; History of stroke and epilepsy ; Inability to remain in the examination position; Recurrent episodes of vertigo or history of previously diagnosed peripheral vestibulopathy; Patients with a pacemaker or any device that may undergo changes resulting from the use of EVG; Cognitive changes justified by some other pathology associated with Parkinson's disease; Individuals who are alienated and unable to answer for their own actions.