Can we treat depression with self-compassion using virtual reality?

Not Applicable

Completed

• Conditions: Depression; Mental and Behavioural Disorders

• Registration Number: ISRCTN57462718
• Lead Sponsor: niversity College London

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-29
• Study Completion: 2024-06-14
• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Current participant inclusion criteria as of 15/05/2024:
1. Adults aged 18 years or older
2. Registered with Camden & Islington IAPT services (Islington site) for low-intensity psychological therapy for depression
3. Clinical caseness of depression (PHQ-9 = 10)
4. Willing and has capacity to provide written informed consent
5. Sufficiently fluent in English to complete assessments and intervention
6. Double vaccinated against Covid-19
7. Able to commit to attend the appointment schedule

Previous participant inclusion criteria:
1. Adults aged 18 years or older
2. Registered with Camden & Islington IAPT services (Islington site) for low-intensity psychological therapy for depression
3. Diagnosis of depression (PHQ-9 score of 10+ and ICD-10 diagnosis of F32 depressive episode on the CIS-R)
4. Willing and has capacity to provide written informed consent
5. Sufficiently fluent in English to complete assessments and intervention
6. Double vaccinated against Covid-19
7. Able to commit to attend the appointment schedule

Exclusion Criteria

Current participant exclusion criteria as of 15/05/2024:
1. Current drug or alcohol dependence
2. Individuals at current risk of suicide or self-harm
3. Individuals with severe depression (PHQ-9 score of 20+)
4. IAPT clinician deemed participation not appropriate
5. Defined as clinically extremely vulnerable (at high risk of serious illness from coronavirus)
6. History of seizures, brain injury or epilepsy
7. Uncorrected hearing or vision impairment
8. Head or neck injury, or individuals suffering from musculoskeletal problems
9. Individuals with vestibular/balance issues
10. Individuals engaging in any concurrent psychological treatments or mental health research

Previous participant exclusion criteria:
1. Current drug or alcohol dependence
2. Individuals at current risk of suicide or self-harm
3. Individuals with severe depression (ICD-10 F32 diagnosis of severe depressive episode and/or PHQ-9 score of 20+)
4. IAPT clinician deems participation not appropriate
5. Defined as clinically extremely vulnerable (at high risk of serious illness from coronavirus)
6. History of seizures, brain injury or Epilepsy
7. Uncorrected hearing or vision impairment
8. Head or neck injury, or individuals suffering from musculoskeletal problems
9. Individuals with vestibular/balance issues
10. Individuals engaging in any concurrent psychological treatments or mental health research during the course of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility and acceptability of a full RCT. This will be assessed by:<br>1. Recruitment rates<br>2. Eligibility rates<br>3. Willingness to be randomized rates<br>4. Retention rates<br>5. Ease of delivery. This will be assessed by engaging in qualitative research with those involved in recruitment and treatment to examine issues of implementation and practicality. <br>6. Acceptability of the intervention and adherence to the intervention protocol. This will be assessed by 1) using the Treatment Acceptability/Adherence Scale questionnaire (TAAS, Milosevic et al., 2015) mid-way through the intervention (end of session 2 out of 4) and 2) engaging in qualitative work with participants (both completing and dropping out).