Characteristics and Outcome of Patients With COVID-19 in ICUs in South Tyrol

Completed

• Conditions: COVID-19 Acute Respiratory Distress Syndrome; COVID-19

• Registration Number: NCT05077319
• Lead Sponsor: Institute of Mountain Emergency Medicine

Brief Summary

The investigators retrospectively investigate the epidemiology, clinical characteristics and therapeutic interventions of patients with COVID-19 associated respiratory failure admitted to the intensive care units in South Tyrol, Italy.

Detailed Description

In this observational, retrospective study the epidemiology, characteristics, therapeutic interventions and outcome of patients with COVID-19 associated respiratory failure admitted to the intensive care units in South Tyrol, Italy, are assessed. Data extracted from the medical patients' records include type and duration of respiratory support (high-flow nasal oxygen, non-invasive ventilation, invasive ventilation), need for tracheostomy, vasopressor needs, antibiotic therapy, corticosteroid treatment, laboratory values (interleukin-6, C-reactive protein, procalcitonin, D-dimer, lymphocyte count), lengths of stay in the ICU and mortality.

Study Timeline

• Study Start: 2020-03-05
• Primary Completion: 2021-09-20
• Status Verified: 2021-10
• Study Completion: 2021-10-04
• Study First Submitted: 2021-10-04
• Study First Submitted QC: 2021-10-12
• Last Update Submitted: 2021-10-12
• Study First Posted: 2021-10-14
• Last Update Posted: 2021-10-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 550

Inclusion Criteria

• All patients admitted to the intensive care units in South Tyrol due to COVID-19 associated respiratory failure

Exclusion Criteria

• SARS-CoV-2 patients admitted to the intensive care units in South Tyrol for other pathologies (i.e., not respiratory failure)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality	Through study completion, an average of 1 year	Mortality (dead/alive) at discharge from the ICU is defined as primary outcome

Trial Locations

Locations (1)

Eurac research; 🇮🇹 Bolzano, Italy