Pleth Variability Index as a Predictor for Post-induction Hypotension in Elderly Patients
- Conditions
- Post-induction Hypotension
- Registration Number
- NCT04886089
- Lead Sponsor
- Cairo University
- Brief Summary
Hypotension after induction of general anesthesia and before surgical stimulation is a prevalent anesthesia-related side effect. The post-induction hypotension disrupts organ perfusion and may cause organ damage particularly acute kidney injury, cerebrovascular stroke, and myocardial ischemia. Post-induction hypotension occurs with greater frequency and severity in the elderly. This is because of aged-related diminished cardiac reserve and impaired autonomic homeostasis. Pleth variability index (PVI) is a software program that measures the dynamic changes of the PI that occurs during a complete respiratory cycle. Our primary outcome is to determine the predictive ability and the optimal cut-off value of pre-anesthesia PVI for predicting elderly patients who are at risk of developing post-induction hypotension
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 85
- patients with ASA physical status I or II
- patients will receive general anesthesia
- Patients with a history of cardiorespiratory disorders
- patients with uncontrolled hypertension or cardiac dysrhythmias
- Patients with renal or hepatic diseases.
- Patients with long-standing diabetes and peripheral vascular diseases.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The accuracy (Area under receiver operating characteristic curves) of pre-induction PVI for prediction of post-induction hypotension before induction of general anesthesia
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Abeer Ahmed Mohamed
🇪🇬Maadi, Cairo, Egypt