跳至主要内容
临床试验/ISRCTN40147207
ISRCTN40147207已完成未知

Bronchoalveolar lavage and biopsy findings in healthy non-smoking individuals

niversity Hospital of South Manchester NHS Foundation Trust (UK)0 个研究点目标入组 30 人开始时间: 2012年1月25日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
30

研究概览

简要总结

2012 results in https://www.ncbi.nlm.nih.gov/pubmed/22978556 (added 10/12/2019)

研究设计

研究类型
Observational

入排标准

性别
All

入选标准

  • 1. Over 18 years of age
  • 2. Normal lung function
  • 3. Negative methacholine challenge (no bronchial hyper-reactivity)

排除标准

  • 1. Recent upper respiratory infection (<4 weeks)
  • 2. Pregnancy / breast feeding
  • 3. Use of inhaled or oral steroids in last three months
  • 4. History of drug or alcohol abuse
  • 5. Chronic respiratory, cardiovascular, gastro-intestinal, haematological, neurological or psychiatric illness or chronic ill health. This includes past histroy at any age of asthma, or current symptomatic rhinitis
  • 6. Symptomatic gastro-oesophageal reflux or post nasal drip, or history of chronic cough
  • 7. History of auto-immunity/diabetes mellitus
  • 8. Current smoker
  • 9. Ex-smoker of < 6 months or >10 pack/year history
  • 10. History of anaphylaxis or known allergy to lignocaine/midazolam/methacholine

研究者

发起方
niversity Hospital of South Manchester NHS Foundation Trust (UK)

相似试验