Comparing the preservation of alveolar bone after tooth extraction by immediate bone grafting with amniotic membrane or collagen membrane

Not yet recruiting

• Conditions: The tooth with endodontic failure or unable to restore from severe caries or crown/root fracture or mobility in maxilla or mandible which are going to be extracted

• Registration Number: CTRI/2021/10/037055
• Lead Sponsor: Aabida Taslim

Brief Summary

Osseointegration andlongevity of implants depend on the quantity and quality of the alveolar ridge atthe time of implant placement. Tooth extraction is led byalveolar bone resorption which rapidly begins and continues for years To eliminate or minimize extensive regenerative surgical procedures, the alveolar ridge preservation (ARP) procedure is recommended to perform at the time of tooth extractionto preserve the alveolar bone architecture.  Alveolar ridge preservation can be achieved by immediately filling the undamaged tooth socket with biomaterials. Different types of bone substitutions and membranes have been utilized for socket augmentation. Our goal is to evaluate the efficacy of the amniotic membrane, as a new material, on in comparison with the collagen membrane in the present study.  In this study, prevention of alveolar bone resorption after tooth extraction by immediate bone grafting with amniotic membrane or collagen membrane.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-01-10
• Study Start: 2021-09-10

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Physically, mentally, and systemically healthy patient.
• Indications for extracting tooth are including single-rooted teeth with endodontic failure or unable to restore from severe caries or crown/ root fracture or mobility.

Exclusion Criteria

• Patients with compromised medical history.
• Presence of dehiscence or fenestration or socket destruction more than 50% of the alveolar bone wall of the socket after extraction 3.
• History of malignancy, radiotherapy, or chemotherapy for malignancy in the past 5years.
• Unwillingness to sign a consent form and return it for all follow-up periods.
• Habits like smoking and chewing 6.
• Parafunctional habits 7.
• Traumatic occlusion 8.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Preservation of horizontal and vertical alveolar ridge dimension in all cases	pre-op, post-op and at 6th month

Secondary Outcome Measures

Name	Time	Method
Prevention of width of keratinized tissue, height free gingival margin, soft tissue thickness, pain, redness and swelling in all cases	pre-op, at 1st month ,at 3rd month and at 6th month

Trial Locations

Locations (1)

Faculty of Dental Sciences IMS BHU; 🇮🇳 Varanasi, UTTAR PRADESH, India

Faculty of Dental Sciences IMS BHU

🇮🇳Varanasi, UTTAR PRADESH, India

Aabida Taslim

Principal investigator

7081354131

aabidataslim1705@gmail.com