IRCT20200331046902N1招募中2 期
Investigation the effect of oral Rosemary hydro-alchohlic extract on chemotherapy induced peripheral neuropathy in the patients with metastatic gastrointestinal malignancy: A randomized clinical trial
Khoram-Abad University of Medical Sciences0 个研究点目标入组 52 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 52
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 25 years 至 80 years（—）
- 性别
- All
入选标准
- •Patients with metastatic gastrointestinal cancers aged 25 to 80 years undergoing chemotherapy with oxaliplatin-containing chemotherapy regimens.
排除标准
- •Patients who have previously received a chemotherapy regimen containing neurotoxic drugs and now have peripheral neuropathy.
- •Patients receiving other neurotoxic drugs (such as some HIV drugs) at the same time as chemotherapy.
- •Patients with a history of diabetes mellitus and peripheral neuropathy caused by nerve compression (such as carpal tunnel or tarsal syndrome, radiculopathy, spinal stenosis, brachial plexopathy)
- •Patients who, at the same time as chemotherapy, start taking drugs that reduce neuropathy symptoms (such as SNRI drugs) and pain relievers such as acetaminophen, pregabalin, and NSIDs, or change their amount during treatment.
- •Patients with psychological disorders such as: severe depression, patients with suicidal thoughts, bipolar diseases
- •Patients who consume alcohol.
- •Patients with significant impairment of liver and kidney tests
- •Patients who do not agree to consume rosemary extract or do not agree to participate in the study in any way.
- •The patient is unable to tolerate rosemary extract during the study.
研究者
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