Influence of an acidic beverage on the absorption of erlotinib
Completed
- Conditions
- lungcancer
- Registration Number
- NL-OMON24483
- Lead Sponsor
- Erasmus University Medical Center
- Brief Summary
van Leeuwen et al. Influence of the Acidic Beverage Cola on the Absorption of Erlotinib in Patients With Non-Small-Cell Lung Cancer. J Clin Oncol. 2016;34(12):1309-14
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 28
Inclusion Criteria
1. Age > 18 years
2. Use of Erlotinib monotherapy for at least 4 weeks
Exclusion Criteria
1. Age < 18 years
2. Pregnant or lactating patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differences in erlotinib bioavailability during coca-cola intake vs. water intake (+/- PPI)
- Secondary Outcome Measures
Name Time Method Toxicity of erlotinib