JPRN-UMIN000008490招募中2 期
Phase II study of S-1 monotherapy as 1st line chemotherapy in patients > or = 80 with advanced non-small cell lung cancer - Phase II study of S-1 monotherapy as 1st line chemotherapy in patients > or = 80 with advanced non-small cell lung cancer
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 35
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 80years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) History of severe hypersensitivity drug reaction 2) Prior radiotherapy to the primary tumor except the radiotherapy to the bone metastasis and the brain metastasis. 3) Patients with administration contraindication to S-1 4) Synchronous cancer, or metachronous cancer with less than 5 years of disease-free interval except carcinoma in situ of the cervix and basal type skin cancer 5) Concomitant active infection 6) Radiographically confirmed interstitial pneumonitis or pulmonary fibrosis 7) Severe complication(s), e.g., renal failure, hepatic failure, poorly controlled diabetes, or poorly controlled hypertension 8) Distinctly abnormal ECG or cardiovascular disease (heart failure, myocardial infarction, angina) 9) Patients with severe diarrhea 10) Pleural and peritoneal likely to require surgical intervention 11) Symptomatic brain metastasis. 12) Concomitant treatment with flucytosine, phenytoin or warfarin 13) Physician concludes that the patient's participation in this trial is inappropriate
研究者
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