Psychophysical Characterization and Brain Correlates of Dentine Hypersensitivity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Subjective ratings using the BORG scale
研究概览
简要总结
Up to date, devices capable of delivering controlled, calibrated, non-contact cold air stimuli in a MR environment are unavailable for quantitative sensory testing. This project therefore aimed at designing and constructing a novel MR-compatible, computer-controlled cold air stimulation device that produces air puffs in a broad flow and cold temperature range. By means of this device, detailed psychophysically testing and subsequent brain scanning of dentine hypersensitivity (DH) subjects will be possible to gain new insights about DH mechanisms.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age and between 18 - 60
排除标准
- •Defective restorations
- •Full crowns
- •Orthodontic bands
- •Bleeding on probing and periodontal pockets deeper than 3 mm
- •Subjects with gross periodontal disease or treatment of periodontal disease in the past 12 months.
结局指标
主要结局
Subjective ratings using the BORG scale
时间窗: May 1, 2016
individual subject perception ratings will be recorded by means of an adapted BORG scale. For reliability, intraclass correlations will be used covering 3-4 measures within a 3-4-weeks period.
blood oxygenation level dependent (BOLD) response
时间窗: October 1, 2016
Changes in blood oxygenation level (indirect measure of neural activity) will be recorded
次要结局
未报告次要终点