Psychophysical Characterization and Brain Correlates of Dentine Hypersensitivity
- Conditions
- Dentine Hypersensitivity
- Interventions
- Other: air puffs
- Registration Number
- NCT02929043
- Lead Sponsor
- University of Zurich
- Brief Summary
Up to date, devices capable of delivering controlled, calibrated, non-contact cold air stimuli in a MR environment are unavailable for quantitative sensory testing. This project therefore aimed at designing and constructing a novel MR-compatible, computer-controlled cold air stimulation device that produces air puffs in a broad flow and cold temperature range. By means of this device, detailed psychophysically testing and subsequent brain scanning of dentine hypersensitivity (DH) subjects will be possible to gain new insights about DH mechanisms.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Age and between 18 - 60
- Caries
- Defective restorations
- Full crowns
- Orthodontic bands
- Bleeding on probing and periodontal pockets deeper than 3 mm
- Subjects with gross periodontal disease or treatment of periodontal disease in the past 12 months.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Dentine hypersensitivity subjects air puffs -
- Primary Outcome Measures
Name Time Method Subjective ratings using the BORG scale May 1, 2016 individual subject perception ratings will be recorded by means of an adapted BORG scale. For reliability, intraclass correlations will be used covering 3-4 measures within a 3-4-weeks period.
blood oxygenation level dependent (BOLD) response October 1, 2016 Changes in blood oxygenation level (indirect measure of neural activity) will be recorded
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Zurich, Center of Dental Medicine
🇨ðŸ‡Zurich, Switzerland