Healthcare for Individuals with Leg Wounds related to circulatory problems: a study testing a treatment with various possibilities

• Conditions: Varicose Ulcer; Wound Healing; I01.800

• Registration Number: RBR-8n3nxg8
• Lead Sponsor: niversidade Federal do Rio Grande do Norte

Brief Summary

Our objective was to assess the effect of Venous Leg Ulcer (VLU) healing on Quality of Life (QoL) in patients undergoing compression therapy. This non-randomized, quasi-experimental, and observational study involved patients with VLU. A convenience sample of individuals receiving services was followed for at least one year, utilizing Unna boot compression therapy. The Medical Outcomes Short-Form Health Survey (SF-36) and the Charing Cross Venous Ulcer Questionnaire (CCVUQ) were employed to measure the variables of interest. Study participants were categorized into the Healed Group (HG) and the Unhealed Group (UG). The final sample comprised 103 individuals. The HG demonstrated improvements in SF-36 scores in the domains of Social Role Functioning (n=34, p<0.001), Physical Role Functioning (n=33, p<0.001), and the Physical Health Dimension (n=38, p<0.001). Additionally, the CCVUQ assessment revealed score enhancements in the domains of Domestic Activities (n=30, p=0.001) and Social Interaction (n=30, p=0.009). QoL exhibited significant enhancements in aspects related to functionality, physical performance, and social interaction in the HG after one year of compression therapy treatment. Conversely, the UG was the only group to show significant deteriorations in QoL.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-11-30
• Study Start: 2024-03-20
• Last Update Posted: 2 April 2024

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Age equal to or greater than 18 years; be registered at any Primary Health Care unit covered by the service; present at least one active venous ulcer

Exclusion Criteria

Individuals with venous ulcers completely healed before the start of the study; those who did not attend appointments for more than one month; those who died or moved to a region outside the coverage area after the first collection; patients with mixed or non-venous leg lesions

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in quality of life after one year of treatment with Unna boot compression therapy.;A total sample of n=43 (43.7%) progressing to healing after one year of treatment (Healing Group - HG);We found that the Non-Healing Group (NHG) showed an increase in the SF-36 score for most individuals in the Social Aspect (n=45), Functional Aspect (n=33), General Health State (n=40), and Pain (n=40) Domains, and a reduction in their scores in the Emotional Aspects Domain (n=40) and Physical Health Dimension (n=50). The HG, in turn, showed an increase in the SF-36 score in the Social Aspect (n=34), Functional Aspect (n=33), and Physical Health Dimension (n=38) Domains, as well as maintaining its score (=) in the Physical Aspect Dimension (n=24, p<0.001).