JPRN-UMIN000026050已完成2 期
Phase II study to assess efficacy, safety & immunological biomarker of anti PD-L1 antibody + anti CTLA-4 antibody in combination with hormone therapy in patients with hormone receptor positive HER2-negative recurrent or metastatic breast cancer - KBCRN-B-001
Breast Cancer Research Network0 个研究点目标入组 33 人开始时间: 2017年2月8日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 33
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- Female
入选标准
- 未提供
排除标准
- •1)Active or prior documented autoimmune disease within the past 2 years. 2)Current or prior use of immunosuppressive medication within 28 days before the first dose of durvalumab or tremelimumab 3)Patients with central nervous system metastasis 4)Patients with life-threatening disease. 5)Patients with a history of treatment with anti-PD-1, anti-PD-L1, anti-PD-L2 or anti-CTLA-4 antibody drug. 6)Patients who have received live vaccination within 30 days before start of the investigational products. 7)Patients with a past medical history of pneumonia requiring steroid treatment or with a past medical history of interstitial pneumonia. 8)Patients considered ineligible for participation in this study by their attending physicians.
研究者
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