Effectiveness of saline-infused sonography and hysteroscopy in the work-up for postmenopausal bleeding.
Completed
- Conditions
- Endometrial polyps, Postmenopausal bleeding.In Dutch: Endometrium Poliepen, Postmenopauzaal bloedverlies.
- Registration Number
- NL-OMON24422
- Lead Sponsor
- Academic Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Women with postmenopausal bleeding and an endometrial thickness of more than 4 mm in whom a malignancy is ruled out by office endometrial sampling.
Exclusion Criteria
1. Women with postmenopausal bleeding during tamoxifen or arimidex treatment;
2. Women with an endometrial sample containing insufficient material for a reliable diagnosis;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The recurrence of postmenopausal bleeding.
- Secondary Outcome Measures
Name Time Method Secondary outcomes are:<br /><br>1. What is the added informativeness of SIS in the diagnosis of endometrial polyps using hysteroscopy as a reference standard?<br /><br>2. What are the costs of transvaginal sonography, SIS and hysteroscopy as well as the costs of recurrent postmenopausal bleeding?