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临床试验/NCT07711665
NCT07711665已完成不适用

Acute Caffeine Intake Effects in Strength and Endurance Performance in Resistance-training-naïve Older Adults

University of Alcala1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2024年1月10日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
36
试验地点
1
主要终点
Mean velocity at different %1RM

研究概览

简要总结

Evidence regarding the ergogenic effects of caffeine is well-established in young adults, but evidence in older adults remains scarce, particularly during dynamic resistance exercise. Therefore, this study investigated the effects of acute caffeine ingestion on upper- and lower-body muscular strength and endurance performance, as well as the influence of sex and CYP1A2 genotype, in healthy resistance training-naïve older adults.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Double (Participant, Investigator)

盲法说明

Statisian

入排标准

年龄范围
55 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 55 years.
  • Body mass index (BMI) lower than 25 kg/m².
  • Physically active subjects (≥150 min/week of moderate exercise).
  • Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from performing physical exercise.
  • Participants capable of performing the tests.

排除标准

  • History of neuromuscular, cardiac, or diseases that could affect liver or muscle metabolism.
  • Use of drugs or other stimulants that interfere with caffeine intake and intestinal absorption during the tests and study.
  • Body mass index (BMI) ≥ 25 kg/m².
  • Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study. • Performing strenuous exercise within 48 hours prior to the tests.
  • Failing to replicate the same food intake on the two experimental days.
  • Consuming caffeine after 6 PM on the day prior to training or testing.

研究组 & 干预措施

Caffeine

Experimental

Acute caffeine intake (3 mg/kg)

干预措施: Caffeine (Dietary Supplement)

Placebo

Placebo Comparator

Placebo (3 mg/kg maltodextrin)

干预措施: Placebo (Dietary Supplement)

结局指标

主要结局

Mean velocity at different %1RM

时间窗: hrough study completion, an average of 3 weeks

Mean velocity at different %1RM

Number of repetitions performed in 1 set at 65%1RM until task failure

时间窗: Through study completion, an average of 3 weeks

In bench press and back squat exercises

Bar velocity deplacement performed in 1 set at 65%1RM until task failure

时间窗: Through study completion, an average of 3 weeks

In bench press and back squat exercises

handgrip and isometric mid-thigh pull tests

时间窗: Through study completion, an average of 3 week

N generated

Mean velocity at different %1RM

时间窗: Through study completion, an average of 3 weeks

Mean velocity at different %1RM

Number of repetitions performed during 1 set at 65%1RM until task failure

时间窗: Through study completion, an average of 3 weeks

In bench press and back squat exercises

次要结局

  • cyp1a2 polymorphism(Before the beginning of the trial)
  • Mood state (tension, depression, anger, vigor, fatigue and confusion)(Through study completion, an average of 3 weeks)
  • Adverse effects(Through study completion, an average of 3 weeks)
  • CYP1A2 polymorphism(Before the beginning of the trial)

研究者

发起方
University of Alcala
申办方类型
Other
责任方
Principal Investigator
主要研究者

Alberto Pérez-López

Principal Investigator

University of Alcala

研究点 (1)

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