A CASE CONTROL STUDY OF PALITYA IN THE CONTEXT OF RASAVAHINI DUSYANTI CINTYANAM CATICINTANAT AND RANDOMIZED CONTROLLED TRIAL OF SHANKHPUSHPI SYRUP AS AN ADD ON THERAPY OF KASMARYADI TAILA
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Changes in GSS (greying severity score) in both groups before and after treatment
研究概览
简要总结
PHASE 1 : Case Control study ( Nidanatmaka study )
Case Control Study :
Research Question:
Is there any association between Rasavahini Dusyanti Cintyanam Caticintanat and Palitya on the basis of perseverative thinking questionnaire?
Hypothesis :
Null Hypothesis : There is no association between Rasavahini Dusyanti Cintyanam Caticintanat and Palitya on the basis of perseverative thinking questionnaire.
Alternate Hypothesis : There is association between Rasavahini Dusyanti Cintyanam Caticintanat and Palitya on the basis of perseverative thinking questionnaire.
AIMS AND OBJECTIVES:
Aim:
To evaluate association between Rasavahini Dusyanti cintyanam caticintanat and Palitya on the basis of perseverative thinking questionnaire.
Objectives :
To find out the association between Rasavahini Dusyanti cintyanam caticintanat and Palitya on the basis of perseverative thinking questionnaire
PHASE 2 : Randomized Comparative Trial
Research Question :
What is the effect of locally applied Kasmaryadi Taila with and without oral administration of Shankhpushpi Syrup in terms of change in Greying Severity Score (GSS) in Palitya before and after treatment that is i.e. day 0, 15, 30?
Hypothesis :
Null hypothesis :
There is no difference between the effect of locally applied Kasmaryadi Tail with and without oral administration of Shankhpushpi Syrup in terms of change in Greying Severity Score (GSS) in Palitya.
Alternate hypothesis :
There is difference between the effect of locally applied Kasmaryadi Taila with and without oral administration of Shankhpushpi Syrup in terms of change in Greying Severity Score (GSS) in Palitya.
AIMS AND OBJECTIVES :
Aim :
To assess the add on effect of orally given Shankhpushpi Syrup with locally applied Kasmaryadi Taila in terms of change in baseline GSS (greying Severity Score) before and after completion of therapy.
Objectives :
Primary Objective:
To compare the therapeutic efficacy of locally applied Kasmaryadi Taila as compared to with and without oral administration of Shankhpushpi Syrup in terms of change in Greying Severity Score (GSS) in Palitya.
Secondary Objective:
To assess the changes in clinical signs and symptoms of Palitya before and after treatment that is i.e. day 0,15,30.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having grey hairs more than 10 % and upto 75 %.
排除标准
- •Individuals with any known hormonal imbalance problems.
- •Any kind of fungal or other infection of scalp.
- •Pregnant ladies.
- •Other skin disorders like Psoriasis, Eczema,Leucoderma, Seborrhic Dermatitis.
- •Individuals of Pitta Pradhan Prakriti.
- •Individuals giving consent to not use dye/hair colour /bleach during the trial period.
结局指标
主要结局
Changes in GSS (greying severity score) in both groups before and after treatment
时间窗: Changes will be observed in 0, 15 and 30 Days
次要结局
- Changes in clinical signs & symptoms of Palitya in both groups before & after treatment(sign & symptoms of Palitya like keÅ›a varṇa (color of the hair), ruká¹£a & sphuá¹ita keÅ›a (Dry & split hair), kapÄladÄha (Burning sensation in the scalp), svedapravá¹›ti on forehead & scalp(sweatning))
研究者
DR ASHA KUMAWAT
National Institute of Ayurveda, Deemed to be University (De-novo)