Comparative efficacy assessment of Tamsulosin vs. Tamsulosin plus Pentoxifylline in the treatment of LUTS/BPH: A preliminary study

Phase 4

Recruiting

• Conditions: Benign Prostate Hyperplasia.; Enlarged prostate with lower urinary tract symptoms; N40.1

• Registration Number: IRCT20210729052012N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

Age>40
International Prostate Symptom Score(IPSS)>13
Prostate Volume>20ml
maximum urinary flow rate(Qmax)<15ml/s
Voided Volume>100ml
creatinine(Cr)<2

Exclusion Criteria

Age<40
history of prostate cancer
renal dysfunction
previous prostate surgery
bladder calculus
active UTI
postvoid residual urine volume of > 250 mL
exposure to sex hormone within 3 months prior
history of severe liver impairment
history of severe cardiovascular diseases
severe hypotension
history of neurogenic bladder
history of urethral stricture

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
International Prostate Symptom Score. Timepoint: At the beginning of the study and 12 weeks after treatment. Method of measurement: International Prostate Symptom Score chart.;Quality of Life. Timepoint: At the beginning of the study and 12 weeks after treatment. Method of measurement: Quality of life due to urinary symptoms chart.;Maximum urinary flow rate. Timepoint: At the beginning of the study and 12 weeks after treatment. Method of measurement: Uroflowmetry.;Voided volume. Timepoint: At the beginning of the study and 12 weeks after treatment. Method of measurement: Uroflowmetry.