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Machine Learning Predict Renal Replacement Therapy After Cardiac Surgery

Completed
Conditions
Prediction Models
Machine Learning
Acute Kidney Injury
Renal Replacement Therapy
Registration Number
NCT04977687
Lead Sponsor
Chinese PLA General Hospital
Brief Summary

Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication which may result in adverse impact on short- and long-term mortality. The researcher here developed several prediction models based on machine learning technique to allow early identification of patients who at the high risk of unfavorable kidney outcomes. The retrospective study comprised 2108 consecutive patients who underwent cardiac surgery from January 2017 to December 2020.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2108
Inclusion Criteria
  • age over 18 years who underwent cardiac surgery
Exclusion Criteria
  • data miss greater than 10%

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
patients required renal replacement therapy14 days

The primary outcome was patients with the requirement for acute dialysis within 14 days after cardiac surgery. Renal replacement therapy is recommended for patients with severe acute kidney injury as well as hemodynamic instability or severe electrolyte disturbances (e.g. blood potassium \> 6) or acid-base balance disturbances (e.g. H value less than or equal to 7.15).

Prior to the start of renal replacement therapy, the investigator invited a consultation with the nephrology department to assess the condition

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Chinese PLA General hospital

🇨🇳

Beijing, Beijing, China

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