The Effects of Topical St Johns Wort Application in Patients with Plaque Type Psoriasis vulgaris
Not Applicable
- Conditions
- Plaque Psoriasis.Psoriasis vulgaris
- Registration Number
- IRCT201503173106N24
- Lead Sponsor
- Islamic Azad University, Pharmaceutical Sciences Branch
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
patients with the age between 18 to 50 years old; diagnosis of mild to moderate plaque type psoriasis on both sides of the body; not being under medical treatment for the past two months.
Exclusion criteria: pregnancy; lactation; suffering from a major illness (such as cardiovascular disease, acute renal or liver disease, cancer or active malignancy); not having plaque psoriasis on both sides of the body.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Erythema, Thickness, Scaling. Timepoint: At the end of week 4. Method of measurement: Modified psoriasis area severity index (PASI) scores.;Tissue TNFa Level. Timepoint: At the end of Week 4. Method of measurement: Mouse anti-human TNFa (28401.111) monoclonal antibody.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: At the end of week 4. Method of measurement: Questionnaire, Photography, Scoring.