Assessment of the effects on 24-hour ambulatory blood pressure and the safety of a once-a-day oral 8 mg perindopril morning administration versus evening administration in hypertensive patients. An 8-week, 2-arm, randomised, double-blind study.
- Conditions
- Essential arterial hyperpertensionMedDRA version: 9.1Level: LLTClassification code 10015488Term: Essential hypertension
- Registration Number
- EUCTR2007-007026-22-CZ
- Lead Sponsor
- Institut de Recherches Internationales Servier
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
Essential hypertension after institution of appropriate healthy lifestyle modification, measured with a validated automatic measurement device in the medical office in supine position: 95 = DBP < 110 mmHg and SBP < 180 mmHg.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Kalaemia = local laboratory's high normal values
Positive pregnancy test for non menopausal women
Creatinine = 150 mmol/l or creatinine clearance < 60 ml/mn, using Cockroft's formula
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method