Early temperature and mortality in critically ill patients with neurological injury.

Not Applicable

• Conditions: Ischamic and Haemorrhagic Stroke, including Subarachnoid Haemorrhage + Traumatic Brain Injury; Central Nervous System Infection; Neurological - Other neurological disorders

• Registration Number: ACTRN12611001218987
• Lead Sponsor: Australian and New Zealand Intensive Care Society Centre for Outcomes and Resource Evaluation

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-11-28
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 20000

Inclusion Criteria

We will include patients with a diagnosis of traumatic brain injury, ischaemic stroke, subarachnoid haemorrhage, intracranial haemorrhage and central nervous system infections according to the coding systems of the ANZICS APD (APACHE III Diagnostic Categories) and the ICNARC Coding Method (ICM).

ANZICS APD Codes: 1601, 601, 409, 1502, 403, 402, 1503, 1501, 401, 404

ICNARC Codes:1.4.2.38.1 to 1.4.2.38.8, 2.4.2.38.1 to 2.4.2.38.8, 1.4.2.15.2, 1.4.2.41.1, 1.4.2.41.2, 2.4.2.15.2, 2.4.2.41.1, 2.4.2.41.2, 2.4.2.41.3, 1.4.2.15.1, 1.4.2.15.3 to 1.4.2.15.4, 2.4.2.15.1, 2.4.2.15.3 to 2.4.2.15.41.4.2.27.1 to 1.4.2.27.3, 1.4.2.27.5 to 1.4.2.27.8, 2.4.2.27.1 to 2.4.2.27.3, 2.4.2.27.5 to 2.4.2.27.8

Exclusion Criteria

Patients admitted following a cardiac arrest due to the confounding effect of therapeutic hypothermia; patients with missing data for either temperature, or admission diagnosis or vital status at hospital discharge; and patients with insufficient information on GCS. Where patients are admitted to ICU more than once during a hospital admission, only the patient’s first admission will be included in the analysis.

Study & Design

• Study Type: Observational
• Study Design: Not specified