Measurement of Retinal Venous Pressure Under Short-term Low-oxygen Environment
Completed
- Conditions
- Healthy
- Registration Number
- NCT01771757
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Brief Summary
The hypothesis is that the pressure in the retinal veins increases under a short-term lack of oxygen and leads to a decreased blood circulation. On the basis of measurements in the hypobaric chamber this hypothesis should be verified.
- Detailed Description
Conduct a pilot study to describe and quantify the retinal venous pressure (RVP) in healthy volunteers under conditions of controlled, reduced ambient and oxygen partial pressure in the pressure chamber of the Aeromedical Institute FAI in Dübendorf, Switzerland. Obtaining evidence of the adaptation behavior of the retinal vascular system in controlled, short-term hypoxic changes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
- healthy
Exclusion Criteria
- eye diseases
- systemic diseases
- term medication (except contraceptives)
- pregnancy
- allergies to the ingredients Alcain, Tropicamide and Phenylephrine
- blood pressure levels except standard (<60 /> 140 mmHg)
- oxygen saturation (SO2) <90%
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Retinal venous pressure 1 hour Quantify the changes in the retinal venous pressure (RVP)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Basel, Dept. of Ophthalmology
🇨🇭Basel, Switzerland