CTRI/2018/10/015912尚未招募Unknown
Role of peri-operative intravenous lidocaine infusion in postoperative pain and recovery following laparoscopic renal surgeries: A randomised control trial
Muljibhai Patel Urological Hospital Nadiad1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2018年1月11日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The primary outcome are the requirement of inhalational agent, postoperative pain intensity and bowel function.
研究概览
简要总结
Patients will be randomized into two groups using computer-generated randomization tables to receive either intraoperative systemic lidocaine infusion (group L) or normal saline (0.9% NaCl) infusion (group C).Approximately 30 minutes before skin incision, patients in group L (n = 40) received an IV bolus (1.5 mg/kg) of 2% lidocaine. This will be followed by a continuous IV infusion of lidocaine at the rate of 1.5 mg/kg/hr until skin closure.The control group (n = 40) will be received the same volume of bolus and continuous infusion of normal saline.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.American Society of Anesthesiologists (ASA) physical status I-III, 2.Undergoing laparoscopic renal surgeries under general anesthesia.
排除标准
- •1.Allergic to local anesthetics 2.Patients with severe underlying cardiovascular disease, 3.Impaired kidney or liver function, 4.History of drug or alcohol abuse, 5.History of chronic pain or daily intake of analgesics, 6.Uncontrolled medical disease (diabetes mellitus and hypertension), 7.History of intake of non-steroidal anti-inflammatory drugs within 24 hours before surgery, 8.Patients with a history of psychiatric disorder, arrhythmia or seizures.
- •9.Nephrectomy for renal transplantation 10.Morbid obesity (BMI > 40).
结局指标
主要结局
The primary outcome are the requirement of inhalational agent, postoperative pain intensity and bowel function.
时间窗: Patient will observed till discharged from the hospital.
次要结局
- Patient comfort and total hospital stay(first followup)
研究者
研究点 (1)
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