Method development - markers for the intake of selected plant foods
- Conditions
- Healthy participants
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 15
Healthy women and men (18-40 years)
- BMI 18.5 - 30 kg/m2
- Good health status
- Written informed consent to participate in the study
- No medical conditions affecting nutrient absorption, digestive function, metabolism or excretion
- Non-smoker
- No regular use of medication (except hormonal contraceptives)
- No intake of antibiotics in the previous 6 months
- No intake of nutritional supplements in the preceding 4 weeks
- No pregnancy or lactation period
- No allergy/ intolerance to food or ingredients of the test meals
- Need to take certain medications during the trial period; the assessment is made by the study physician
- Occurrence of unacceptable adverse events
- Withdrawal of consent to participate in the study
- Non-compliance with the instructions in the study protocol (including hygiene measures) the hygiene measures)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Analysis of the specific increase or specific occurrence of metabolites/marker candidates in urine derived from the tested plant food after a single consumption of the test food compared to the fasting urine sample using untargeted LC-MS-based metabolomics methods.
- Secondary Outcome Measures
Name Time Method Determination of the expected concentration range for the selected marker candidates in the urine of participants, and, if possible, identification of new marker candidates in the urine for the consumed foods using LC-MS based methods.