Incidental Coronary Calcification Quality Improvement Project
试验速览
- 阶段
- 不适用
- 入组人数
- 173
- 试验地点
- 2
- 主要终点
- Rate of Statin Prescription
研究概览
简要总结
This is a multi-center, randomized quality improvement project. At least 200 statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental coronary artery calcium (CAC) on a prior non-gated chest CT will be enrolled across the Stanford Healthcare System and the Palo Alto Veteran's Affairs Healthcare System. Patients will be randomized in a 1:1 fashion to notification or usual care arms. The primary aim of this project is to estimate the increase in 6-month statin prescription among statin-naïve patients without a history of atherosclerotic cardiovascular disease with incidental CAC on a non-gated chest CT who are randomized to receive notification of their findings vs. usual care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non-gated chest CT between 2014-2019
- •The presence of CAC confirmed by manual review by an experienced radiologist
- •Stanford affiliated primary care provider or endocrinologist for Stanford healthcare system patients and VA primary care provider for VA patients with at least 1 encounter since 2018
排除标准
- •Current or prior statin or PCSK9 inhibitor therapy
- •Prior diagnosis of ASCVD (coronary artery disease, peripheral arterial disease, cerebrovascular disease, coronary/peripheral revascularization)
- •Prior coronary imaging (cardiac CT, invasive coronary angiography)
- •Metastatic cancer or active cancer undergoing chemotherapy
- •History of medical nonadherence
结局指标
主要结局
Rate of Statin Prescription
时间窗: Within 6 months
Proportion of patients prescribed a statin
次要结局
- Number of primary Care Clinical Encounters(6 months)
- Number of Cardiology Referrals(6 months)
- LDL Cholesterol Level(6 months)
- Systolic Blood Pressure(6 months)
- Hemoglobin A1c Level(6 months)
- Statin Intensity(6 months)
- HDL Cholesterol Level(6 months)
- Rate of Aspirin Prescription(6 months)
- Total Cholesterol Level(6 months)
- Number of Cardiovascular Diagnostic Tests(6 months)
- Triglyceride Level(6 months)
- Number of Hypertension Medications(6 months)
- Body Mass Index(6 months)
- Pooled cohort equations estimated 10-year risk of atherosclerotic cardiovascular disease(6 months)
研究者
Alexander Sandhu
Principal Investigator, Instructor of Medicine, Division of Cardiology
Stanford University