Alterations in the Cytokine Profile of Premature Infants After Human Milk Fortifier
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Cytokine profile pre and post initiation of HMF
研究概览
简要总结
This is a research study investigating if adding human milk fortifier to a preterm babies breast milk feedings affects the baby's immune system.
详细描述
In very low birth weight (VLBW) infants and preterm infants human milk fortifier (HMF) is often added to breast milk feedings in order to add extra calories, vitamins, and minerals. It is well known that breast milk feedings are easier to digest and have immune benefits compared to formula feedings. Cytokines, marker of immune function, can be found in blood, stool, and breast milk. This study involves collection of blood and stool samples to monitor cytokines. The purpose of this study is to understand whether human milk fortifier alters infants' cytokines.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 6 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Infants born weighing less than 1500 grams
- •exclusive breast milk feedings with intention to fortify with human milk fortifier
排除标准
- •positive blood culture
- •history of necrotizing enterocolitis
- •significant lung disease at the start of the study
结局指标
主要结局
Cytokine profile pre and post initiation of HMF
时间窗: up to 14 days
次要结局
未报告次要终点