“RANDOMIZED CONTROLLED CLINICAL TRIAL OF SHADBINDU TAIL NASYA AND SARIVADI LEPA IN ARDHAVABHEDAKA WITH SPECIAL REFERENCE TO MIGRAINE”

Migraine has become a global issue with global prevalence of 14.7 %. In Asian countries including India average prevalence of migraine is 14 – 20 %. In females’ prevalence rate is goes beyond 25%. Chronic migraine affects approximately 2% of the world population. Migraine and chronic headache are found to be the second most frequently identified cause of short-term absence for non-manual employees, and amongst the five leading causes of emergency department visits. Migraine remains undiagnosed and undertreated in at least 50% of patients, and less than 50% of migraine patients consult a physician . Migraine ranks sixth highest cause of the disease burden as per the years lived with disability (YLD) criteria.

In modern science there are different modalities present for the treatment of migraine, but they aren’t satisfactory as they don’t relive disease completely & providestemporary relief also chances of recurrence are more hampering patient physically, mentally & economically also. Ayurveda shows a promising way for the treatment of migraine (ardhavabhedaka). There are many shamana chikitsa & shodhana chikitsa are described in ayurveda texts.

In Ayurveda Nasya therapy is considered as one of the most promising treatment for all the urdhwajatrugat vikaras. Nasya karma involve administration of herbal oil/drugs/liquids into the nostrils which removes the blockages of the nasal pathways, reduces feeling of heaviness in head region & relief mental stress. These effect of Nasya gives significant relief in diseases associated with nose & head region such as; migraine (Ardhavbhedaka).

Shadbindu tail is proven drug in Ardhavabhedaka with efficacy of approximately 60%. Shadbindu tail is mentioned in Bhavaprakash madhyam khanda 2 shirorogadhikar and gadanigraha part 2 tail prakaran13. SARIVADI LEPA is mentioned in Sushrut Samhita Uttarsthan 26/34. It is also mentioned in SHARANGDHAR SAMHITA 3/11/23 and YOGRATNAKAR shirorog chikitsa with some modification in drugs. Sarivadi lepa is selected as add on effect on shadbindu tail to increase its efficacy. Lepa is easy for application and all drugs in this lepa are easily available and very cost effective. Till today no research has been carried out on SARIVADI LEPA.