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A study of immune imbalance in migraine patients

Not Applicable
Conditions
Health Condition 1: G439- Migraine, unspecified
Registration Number
CTRI/2022/08/044663
Lead Sponsor
Sri Ramachandra Institute of Higher Education and Research D
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Migraine with aura (MWA) and Migraine without aura (MWOA) patients

2.Patients above 18 years old

3.Patients affected by COVID-19

4.Patients who have all been vaccinated against COVID-19, either with both doses or a single dose

Exclusion Criteria

1.Patients with additional comorbidity conditions were not allowed to participate.

2.Patients who have recently taken any immunosuppressants

3.Pregnant women were excluded

4.Patients with previous head injury

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
This study will identify the <br/ ><br>1. Autoantibody levels in migraine patients using various antibody tests and will confirm the immune dysfunction during migraine attacks in patients. <br/ ><br>2. The specific mutation of FOXP3 gene in migraine patients using RT-PCR assay which will be helpful to us to understand on the pathophysiology of migraine.Timepoint: Investigation of 6 months
Secondary Outcome Measures
NameTimeMethod
Secondary outcome include the detection of autoantibody level and FOXP3 gene specific mutation which will give better understanding of migraine as an autoimmune disorderTimepoint: Investigation of 1 year
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