Evaluation of the systemic use of Lycopene supplementation on non-surgical periodontal treatment

Phase 3

Conditions: chronic periodontitis.
Chronic periodontitis
K05.3

Registration Number: IRCT20230830059303N1

Lead Sponsor: Yazd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 42

Inclusion Criteria

the patient is systematically healthy
CAL is more than 3 mm and clinical signs of gingivitis such as erythema and BOP are present.
The patient should not smoke cigarettes or other types of tobacco products.
The patient does not have any history of periodontal treatment in the last 6 months.
Absence of disease or systemic conditions that interfere with wound healing.
Absence of inflammatory conditions in the oral mucosa such as aphthous ulcers and lichen planus and acute allergic reactions
Not using drugs that affect periodontium (anticonvulsants, calcium channel blockers and immunosuppressors)
Not taking antioxidant supplements such as Vitamin C or melatonin
Not allergic to tomatoes
The patient should not be treated with radiotherapy etc.
Not being pregnant or breastfeeding or not receiving hormonal drugs
Not taking anti-inflammatory drugs such as ibuprofen and...

Exclusion Criteria

Non-attendance of the patient in the follow-up sessions
Failure to follow instructions for taking oral lycopene supplements
Failure to observe oral hygiene

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical attachment level. Timepoint: baseline , 4weeks and 8 weeks after using supplement. Method of measurement: periodontal probe.;Periodontal pocket depth. Timepoint: baseline, 4weeks and 8 weeks after using supplement. Method of measurement: periodontal probe.;Bleeding index. Timepoint: baseline, 4weeks and 8 weeks after using supplement. Method of measurement: percentage of bleeding sites.

Secondary Outcome Measures