A Retrospective Study of the Effects of Ocular Acupuncture on Ocular Motor Nerve Palsy

• Conditions: Oculomotor Nerve Palsy; Abducens Nerve Paralysis; Trochlear Nerve Palsy
• Interventions: Other: Ocular acupuncture

• Registration Number: NCT03461809
• Lead Sponsor: First Affiliated Hospital of Harbin Medical University

Brief Summary

This retrospective observational study is designed to assess the response to treatment with ocular acupuncture and its relative factors, in terms of diplopia status, ocular motility differences, and clinical features, in ocular motor nerve palsy patients. During this study, a retrospective data collection will be carried out using the information contained in the medical record of aimed patients, provided that the treatment with ocular acupuncture.

Detailed Description

Not available

Study Timeline

• Status Verified: 2018-02
• Study First Submitted: 2018-02-04
• Study First Submitted QC: 2018-03-05
• Last Update Submitted: 2018-03-05
• Study First Posted: 2018-03-12
• Last Update Posted: 2018-03-12
• Study Start: 2018-03-15
• Primary Completion: 2018-05-15
• Study Completion: 2018-05-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 900

Inclusion Criteria

• Age over 18 years old
• Patient who received at lease 1 times of ocular acupuncture treatment
• Patient who received full set of ophthalmology & neurology assessment pre- and post-treatment.

Exclusion Criteria

• patient who combined with extraocular muscles diseases, eg.thyroid eye disease
• patient who underwent periocular surgery
• patient who combined with congenital ocular motor nerve palsy, eg. Brown syndrome.
• patient who had untreated condition which may lead to ocular motor nerve palsy such as intracranial aneurysm and brain tumor.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Ocular motor nerve palsy treated by ocular acupuncture	Ocular acupuncture	Ocular motor nerve palsy patients who received ocular acupuncture treatment

Primary Outcome Measures

Name	Time	Method
Clinical efficacy rate (Cure, Effective and Invalid)	Through study completion, an average of 1 month.	Clinical efficacy rate (Cure, Effective and Invalid) assessed by investigator's discretion. Efficacy rate is calculated as number of patients with Cure and effective proportional to number of all cases.

Secondary Outcome Measures

Name	Time	Method
Diplopia angle	Through study completion, an average of 2 weeks.	Patient's diplopia angle obtained by retrospective chart review.
Eyeball movement distance	Through study completion, an average of 2 weeks.	Patient's eyeball movement distance obtained by retrospective chart review.
Distance between upper and lower eyelid.	Through study completion, an average of 2 weeks.	Patient's distance between upper and lower eyelid obtained by retrospective chart review.