Randomized Comparative Clinical Evaluation Of Brahmi Taila Nasya And Yoga Module in Chittodvega (Generalized Anxiety Disorder)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- complete remission-100% relief
研究概览
简要总结
Generalized anxiety disorder (GAD) is a mental health disorder that produces fear, worry and a constant feeling of being overwhelmed. It is characterized by excessive, persistent and unrealistic worry about everyday things. A wide range of psychiatric conditions have been described in Ayurveda. Ayurveda follows psychosomatic approach of health. According to Ayurveda psychic factors are involved in almost all the disease processes along with physical disturbance as both are interdependent. Mind is one of the substratums of diseases and having its own Doshas (Rajasa and Tamasa). Many psychological conditions caused by these Doshas like-Kama (passion), Krodha(anger), Lobha (greed), Moha (confusion), Irshya (envy), Mana (conceit), Mada (arrogance), Chittodvega (anxiety), Bhaya (fear), Harsha (exhilaration) etc. Chittodvega is a Manas Vikara mentioned by Charaka which is considered as a perfect word for highlighting the status of anxiety, Generalized Anxiety Disorder. Chittodvega can exists as a separate disease or can be an etiological factor for other psychic and psychosomatic diseases.Being an alarming disease, it requires effective management. In recent years several synthetic drugs have been introduced for the treatment of anxiety disorders. Though these drugs have better results but one cannot avoid major side effects such as drug dependence, drug resistance, sedation etc. Nasya Karma is the main therapeutic measure of Urdhva Jatrugata Roga. Chittodvega is a Mansik Vikara. Mana is said to be located between Shirah and Talu. All organs, which are above the clavicle, are considered as Urdhvanga e.g., Nasa ,Mukha, Netra and Shirah, without Nasya Karma it is not possible to eliminate the vitiated Doshas, which are situated in the Shirah or Nasa etc.Hence Nasya therapy would have significant role in the treatment of the *Chittodvega.*Yoga reduces stress and anxiety by improving autonomic functions via triggering neurohormonal mechanisms that suppress sympathetic activity through downregulation of the hypothalamic–pituitary–adrenal (HPA) axis. Hence Nasya and Yoga moduleare selected for the present study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)(—)
入选标准
- •Patient fulfilling DSM 5 ,diagnostic criteria for GAD Age group between 20-50 years Gender-Irrespective of gender Patient fit for Nasya and Yoga Willing to give written consent.
排除标准
- •Patient presenting with major illness and psychotic disorders Uncontrolled cases of hypertension Uncontrolled cases of type 1 and type 2 diabetes mellitus Severe cardiac diseases like MI,CAD,IHD Pregnant women Not willing to give written consent.
结局指标
主要结局
complete remission-100% relief
时间窗: At Baseline, 4weeks
Markedly improvement-76-99% relief
时间窗: At Baseline, 4weeks
Moderately improvement-51%-75% relief
时间窗: At Baseline, 4weeks
Mild improvement-26-50% relief
时间窗: At Baseline, 4weeks
次要结局
- Assessment of sign and symptoms(31 days)
研究者
Dr Krishna Kumar Sharma
Uttarakhand Ayurved University,Rishikul Campus,Haridwar
