Impact of Health Lifestyle on Body Weight Post Cessation of Pharmacotherapy in Obese Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 128
- 试验地点
- 1
- 主要终点
- Change in body weight
研究概览
简要总结
Pharmacotherapy becomes an important and effective approach to improve body weight. However, it still remains unclear how to manage potential fluctuation after its cessation. Lifestyle change is the foundation and included as a part of clinical routine in real-world, therefore, we plan to conduct a prospective study to assess the impact of health lifestyle education and related lifestyle adherence on body weight in Chinese people who live with obesity or overweight and are off-pharmacotherapy trial. The aim of this study is to examine the impact of lifestyle education and related lifestyle adherence on body weight related parameters in 6 months from treatment. In addition, body weight related results will be described.
详细描述
Novel pharmacotherapy is emerging, leading to substantial and sustained improvement in body weight compared with placebo in clinical trials. However, there is no evidence on management of body weight in real world setting after cessation of treatment. Body weight fluctuation is a pivotal difficulty for obese subjects who left off pharmacotherapy. It would be interesting to investigate the impact of lifestyle education and related lifestyle adherence in this clinical situation and explore factors associated with weight loss maintenance. Therefore, we will conduct a prospective study to assess the impact of lifestyle education and related lifestyle adherence on body weight in Chinese people who live with obesity or overweight and are off-pharmacotherapy trial. The aim of this study is to examine the impact of lifestyle education and related lifestyle adherence on body weight related parameters in 6 months from pharmacotherapy cessation. In addition, body weight related results will be described.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who completed a pharmacotherapy trial with clinically meaningful weight loss (≥5%)
- •Those who consent to this study
排除标准
- •Those who do not consent to this study
研究组 & 干预措施
Lifestyle Education Group
Participants chose to receive a structured remotely delivered lifestyle education program during the 26-week weight loss maintenance period.
干预措施: Lifestyle Education Program (Behavioral)
Non-Education Group
Participants chose not to receive the structured lifestyle education program during the 26-week weight loss maintenance period.
结局指标
主要结局
Change in body weight
时间窗: 6 months
To examine the change in body weight from baseline to 6 months following lifestyle education.
次要结局
- Change in blood lipids(6 months)
- Change in glycemic control(6 months)
- Change in blood pressure(6 months)