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Clinical Trials/NCT01074684
NCT01074684
Completed
Not Applicable

Defining Predictive Factors of Clinical, Laboratory and Imaging Criteria Routinely Used in the Diagnosis of Thyroid Cancer: Observational, Prospective Multicentered Study

National Cancer Institute, Naples8 sites in 1 country959 target enrollmentJanuary 2010
ConditionsThyroid Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Thyroid Cancer
Sponsor
National Cancer Institute, Naples
Enrollment
959
Locations
8
Primary Endpoint
positive predictive value of preoperative suspicious clinical, laboratory and imaging findings
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this study is to describe the correlation between the cytohistology exam of patients undergoing thyroid surgery, and the predictive values of: suspicious clinical findings, preoperative thyroid imaging, and the incidence of thyroid cancer in cytologically negative nodes.

Registry
clinicaltrials.gov
Start Date
January 2010
End Date
December 1, 2021
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
National Cancer Institute, Naples
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Consecutive patients presenting for thyroid disease (palpable nodules)
  • Indication for surgery
  • Age \> 18 years
  • Signed informed consent for surgery
  • Signed informed consent for data collection

Exclusion Criteria

  • Concurrent condition that contraindicates surgery
  • Clinical or radiologic evidence of locally advanced tumor
  • Clinical or radiologic evidence of metastatic lymph nodes or distant metastases
  • Nonpalpable nodes

Outcomes

Primary Outcomes

positive predictive value of preoperative suspicious clinical, laboratory and imaging findings

Time Frame: at baseline

Study Sites (8)

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