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Clinical Trials/CTRI/2025/04/084150
CTRI/2025/04/084150
Completed
Phase 1/2

Comparative Evaluation of Injectable Platelet-Rich Fibrin with and without Aloe Vera for Hair Retention and Growth in Androgenic Alopecia: A Pilot Study

Murtaza Contractor1 site in 1 country5 target enrollmentStarted: April 20, 2025Last updated:
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Overview

Phase
Phase 1/2
Status
Completed
Sponsor
Murtaza Contractor
Enrollment
5
Locations
1
Primary Endpoint
Hair growth in group where AloeVera is adjunct to i-PRF shpws better result than i-PRF alone
OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Overview

Brief Summary

i-PRF has sown very promissing result in-vitro with increasing concentration in direct proportion. Aloe vera on the other hand showed that it needs an optimum concentration to get optimum outcomes. 100% pure aloevera showed cell death. so as per the optimum concentration achieved in an in-vitro study, aloevera is formulated and it is now checked in this in-vivo study with a split scalp method.

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
20.00 Year(s) to 40.00 Year(s) (—)
Sex
Male

Inclusion Criteria

  • •Norwood Hamilton classifications III to V, and no history of hair restoration therapy in the preceding six months.

Exclusion Criteria

  • •Patients with active scalp infections, systemic diseases, or known hypersensitivity to Aloe Vera were excluded.

Outcomes

Primary Outcomes

Hair growth in group where AloeVera is adjunct to i-PRF shpws better result than i-PRF alone

Time Frame: outcome will be assessed at baseline and after 12 weeks

Secondary Outcomes

  • i-PRF with Aloe Vera will not show better result than i-PRF alone(outcome wil be assessed after 12 weeks)

Investigators

Sponsor
Murtaza Contractor
Sponsor Class
Private hospital/clinic
Responsible Party
Principal Investigator
Principal Investigator

Murtaza Contractor

Dr. D. Y. Patil Dental College and Hospital

Study Sites (1)

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