Fatigue, Psychological Comorbidity and Quality of Life Among Patients With Chronic Pancreatitis in China.
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- The incidence of anxiety among patients with CP in China.
研究概览
简要总结
This study will investigate the status of fatigue, psychological comorbidity and quality of life among patients with chronic pancreatitis in China and analyze their influencing factors.
详细描述
Chronic pancreatitis (CP) is an inflammatory disease characterized by pancreatic fibrosis. Available studies suggested that the incidence of CP in China was about 13.5 per 100,000 people. Patients with CP often have symptoms of pancreatic endocrine and exocrine insufficiency such as elevated blood sugar, weight loss, muscle loss, combined with complications such as pancreatic duct stones, pancreatic duct stenosis, pancreatic pseudocysts, and have a higher risk of pancreatic cancer, which seriously affects the quality of life of patients.
Psychological comorbidities represented by anxiety and depression were thought to be widespread in CP patients, with available epidemiological studies indicating that the prevalence of anxiety and depression in CP patients in the United States was 36.8% and 46.8%, respectively. In addition, fatigue, as a subjective perception of decreased ability to perform physical and/or intellectual tasks, has also been founded among CP patients.
However, to date, there is a lack of epidemiological studies on fatigue, anxiety, depression and quality of life in Chinese patients with CP. This study will investigate the epidemiological status of fatigue, anxiety, depression, and quality of life in Chinese patients with CP and analyze the factors influencing them.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of chronic pancreatitis
排除标准
- •Illiterate
- •Having communication difficulties
- •Unable to complete the questionnaires
- •Having a history of psychiatric disorders
- •Recent history of psychotropic and sedative drug use
- •Pregnancy
- •Rejected participants
结局指标
主要结局
The incidence of anxiety among patients with CP in China.
时间窗: Within 1 month after data analysis.
The level of anxiety in CP patients is measured using the Hospital Anxiety and Depression Scale (HADS), and the Zung Self-Rating Anxiety Scale (SAS).
The incidence of depression among patients with CP in China.
时间窗: Within 1 month after data analysis.
The level of anxiety in CP patients is measured using the Hospital Anxiety and Depression Scale (HADS), and the Zung Self-rating Depression Scale (SDS).
The incidence of quality of life among patients with CP in China.
时间窗: Within 1 month after data analysis.
The level of quality of life in CP patients is measured using the European organization for the research and treatment of cancer QOL questionnaire (EORTC-QLQ C-30).
The incidence of fatigue among patients with CP in China.
时间窗: Within 1 month after data analysis.
The level of fatigue in CP patients was measured using the Multidimensional Fatigue Inventory (MFI-20), and the Fatigue Severity Scale (FSS).
次要结局
- The influencing factors of anxiety and depression among patients with CP in China.(Within 1 month after data analysis.)
- The influencing factors of depression among patients with CP in China.(Within 1 month after data analysis.)
- The influencing factors of fatigue among patients with CP in China.(Within 1 month after data analysis.)
- The influencing factors of quality of life among patients with CP in China.(Within 1 month after data analysis.)