JPRN-UMIN000019625已完成未知
The mechanism of action of anti-inflammatory effects of propofol in macrophages - The mechanism of action of anti-inflammatory effects of propofol in macrophages
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 6
研究概览
简要总结
Propofol suppresses the progression of inflammation through the attenuation of IL-6 and IL-1-beta production in human M1 macrophages. Nrf2 is involved in the inhibitory activity of propofol via GABAA receptor during M1 polarization. Therefore, propofol administration can suppress postoperative inflammation following invasive surgical procedures.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 70years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •Patients with diabetes mellitus , hyperlipidemia , autoimmune diseases , have a steroid oral
研究者
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