Faecal Microbiota Analysis in Neurotypical and Autism Syndrome Disorder Siblings: FAMILY

East Suffolk and North Essex NHS Foundation Trust1 个研究点分布在 1 个国家目标入组 20 人2022年12月20日

适应症Autism Spectrum Disorder Autism

干预措施Stool sample

概览

阶段: 不适用
干预措施: Stool sample
疾病 / 适应症: Autism Spectrum Disorder
发起方: East Suffolk and North Essex NHS Foundation Trust
入组人数: 20
试验地点: 1
主要终点: Gut microbiota
状态: 已完成
最后更新: 2个月前

概览研究者入排标准研究组 & 干预措施结局指标研究点相似试验

概览

简要总结

This study aims to accurately characterise the gut microbiota composition of faeces of children with ASD and compare it with the gut microbiota composition of their neurotypical siblings. In addition it aims to also characterise the metagenome and metabolome of the faeces of both ASD and neurotypical siblings.

注册库

clinicaltrials.gov

开始日期

2022年12月20日

结束日期

2024年4月12日

最后更新

2个月前

研究类型

Observational

性别

All

研究者

发起方

East Suffolk and North Essex NHS Foundation Trust

责任方

Sponsor

入排标准

入选标准

•Children of both sexes who are diagnosed with ASD and under the care of ESNEFT who have a neurotypical sibling (either full or half sibling), who share their living environment. This is due to the study requiring stool samples that are from siblings, to control for genes and environment where possible.
•Aged 3 years to 10 years old (at time of consent)
•Parent/guardian able to consent to participate
•Parent/guardian able to complete required surveys (or with accommodated adjustments)

排除标准

•Use of antibiotics in the previous 4 weeks
•Not under the care of ESNEFT
•Children \<3 years old and \>10 years old
•Children that don't have half or full siblings
•Parent/guardian unable to provide informed consent or complete surveys, despite reasonable adjustments being implemented