TO STUDY THE RELATION OF ALKALINE PHOSPHATASE ENZYME ACTIVITY IN GINGIVAL CREVICULAR FUILD WITH THE RATE OF TOOTH MOVEMENT FASTENED BY PLATELET RICH PLASMA INJECTIO
Not Applicable
- Conditions
- Health Condition 1: K088- Other specified disorders of teethand supporting structures
- Registration Number
- CTRI/2021/09/036459
- Lead Sponsor
- DR BHARAT KRISHNAN C K
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
class I bimaxillary malocclusion needing all first premolar extractions
Exclusion Criteria
Patients under any other medication which affects tooth movement
Patients with craniofacial anomalies
Patients with periodontal disease
Patients with any kind of systemic disease that affects tooth movement
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The level of ALP in the GCF of experimental side canine and molar and control side canine is evaluated.Timepoint: The GCF samples from the experimental canine and molar and control canine will be evaluated for the ALP levels using Human ALP ELISA test kit at T0(baseline), T1(21st day), T2(3rd month).
- Secondary Outcome Measures
Name Time Method 1.The rate and amount of tooth movement in Platelet rich plasma administered side and non administered side <br/ ><br> <br/ ><br>2.The anchorage loss on the experiment and non experiment side.Timepoint: 1.The amount and rate of tooth movement will be measured from the distal surface of canine and mesial surface of the second premolar at T0(before start of retraction), T1(1st month),T2(2nd month),T3(3rd month) and T4(4th month) <br/ ><br> <br/ ><br>2.The lateral cephalogram will be taken at T0(baseline) and <br/ ><br>T1(3rd month)to assess the position of molar with respect to any stable landmark