Ionized Magnesium for Monitoring of Citrate-anticoagulated CVVHD

Completed

• Conditions: Intensive Care Unit Syndrome

• Registration Number: NCT04412980
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

It has been reported in several studies that ionized hypomagnesemia is associated with higher morbidity and mortality rates. During continuous renal replacement therapy with regional citrate anticoagulation (CRRT-RCA), the loss of magnesium has been reported to not be covered by magnesium concentration in ordinary dialysis fluid. This may lead to ionized hypomagnesemia. However the incidence of ionized hypomagnesemia in patients requiring CRRT-RCA remains unclear and need to be estimated to determine if ionized magnesium monitoring could be of interest. This study aim to assess the incidence of ionized hypomagnesemia induced by CRRT-RCA.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-05
• Study Start: 2020-05-01
• Study First Submitted: 2020-05-18
• Study First Submitted QC: 2020-06-01
• Study First Posted: 2020-06-02
• Primary Completion: 2020-10-01
• Study Completion: 2020-11-23
• Last Update Submitted: 2020-11-23
• Last Update Posted: 2020-11-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
assess the systemic ionized magnesemia change after 24h of CRRTsystemic variations of iMg	Day 0 and Day 1	assess the systemic ionized magnesemia change after 24h of CRRT wiith regional citrate anticoagulation

Secondary Outcome Measures

Name	Time	Method
Assessment of morbidity and mortality	1 day	Assessment of morbidity and mortality
Proportion of patients with heart rhythm disturbances	1 day	Proportion of patients with heart rhythm disturbances

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France