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临床试验/NCT04412980
NCT04412980已完成不适用

Importance of Ionized Magnesium Measurement for Monitoring of Continuous Venovenous Haemodialysis With Citrate Anticoagulation

University Hospital, Montpellier1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2020年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
assess the systemic ionized magnesemia change after 24h of CRRTsystemic variations of iMg

研究概览

简要总结

It has been reported in several studies that ionized hypomagnesemia is associated with higher morbidity and mortality rates. During continuous renal replacement therapy with regional citrate anticoagulation (CRRT-RCA), the loss of magnesium has been reported to not be covered by magnesium concentration in ordinary dialysis fluid. This may lead to ionized hypomagnesemia. However the incidence of ionized hypomagnesemia in patients requiring CRRT-RCA remains unclear and need to be estimated to determine if ionized magnesium monitoring could be of interest. This study aim to assess the incidence of ionized hypomagnesemia induced by CRRT-RCA.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

assess the systemic ionized magnesemia change after 24h of CRRTsystemic variations of iMg

时间窗: Day 0 and Day 1

assess the systemic ionized magnesemia change after 24h of CRRT wiith regional citrate anticoagulation

次要结局

  • Assessment of morbidity and mortality(1 day)
  • Proportion of patients with heart rhythm disturbances(1 day)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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