NCT00038077已完成3 期
Reversal of Ventricular Remodeling With Toprol-XL
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 300
- 试验地点
- 44
研究概览
简要总结
The purpose of this study is to determine whether treatment with Toprol-XL for 12 months in asymptomatic heart failure subjects will improve their heart structure and thus prevent the progression to symptomatic disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of stable asymptomatic heart failure.
- •Documented ejection fraction less than 0.
- •Must be able to comply with all study procedures.
排除标准
- •Taken B-blocker therapy for longer than 1 week within 6 months prior to randomization.
- •Have heart problems that would not allow B-blocker therapy.
- •Receiving B-blockers therapy for any medical reason including topical B-blockers that might cause systemic absorption (e.g., glaucoma).
- •Undergone certain heart surgeries, such as, prior heart transplant or cardiomyoplasty.
- •Have certain heart diseases.
- •Pregnant or breast feeding.
- •Unlikely to survive.
研究者
研究点 (44)
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